For political humor site Destonio I installed Gallery, a photo album organizer developed by the open source community. Gallery has been around for some time, is built well and has been audited by external security experts. Setup was a breeze after unpacking, setting permissions and creating a MYSQL database. It comes with a few design themes which can easily be tweaked through CSS and template files. It comes with many other features like commenting and a rating system. There's an abundance of plugins to add additional features. Cost: free or you can make a donation to the developers after you've determined Gallery is the right application for you.